Vasopressin-vermittelte Wasserrückresorption im Sammelrohr der Niere

Abstract Vasopressin-mediated water reabsorption from primary urine in the renal collecting duct is essential for regulating body homeostasis and depends on channel aquaporin-2 (AQP2). Dysregulation of process can cause balance disorders. Here, we present cell-based high-throughput screenings to identify proteins small molecules as tools elucidate molecular mechanisms underlying AQP2 control potential starting points development disorder drugs.